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The Laboratorial Diagnosis of Dengue: Applications and Implications
The diagnosis of infection by the dengue virus relies, in most cases, on the clinical judgment of the patient, since only a few major centers have clinical laboratories that offer diagnostic tests to confirm the clinical impressions of an infection. At present, routine laboratory diagnosis is done b...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840934/ https://www.ncbi.nlm.nih.gov/pubmed/20300385 http://dx.doi.org/10.4103/0974-777X.52980 |
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author | Dutra, Nina Rocha de Paula, Marília Barbosa de Oliveira, Michelle Dias de Oliveira, Leandro Licursi De Paula, Sérgio Oliveira |
author_facet | Dutra, Nina Rocha de Paula, Marília Barbosa de Oliveira, Michelle Dias de Oliveira, Leandro Licursi De Paula, Sérgio Oliveira |
author_sort | Dutra, Nina Rocha |
collection | PubMed |
description | The diagnosis of infection by the dengue virus relies, in most cases, on the clinical judgment of the patient, since only a few major centers have clinical laboratories that offer diagnostic tests to confirm the clinical impressions of an infection. At present, routine laboratory diagnosis is done by different kinds of testing. Among them are the methods of serological research, virus isolation, detection of viral antigens, and detection of viral genomes. The continued development of diagnostic tests, which are cheap, sensitive, specific, easy to perform, and capable of giving early diagnosis of the dengue virus infection is still a need. There are also other obstacles that are not specifically related to the technological development of diagnostic methods. For instance, infrastructure of the laboratories, the training of personnel, and the capacity of research of these laboratories are still limited in many parts of Brazil and the world, where dengue is endemic. Clinical laboratories, especially the ones that serve regions with a high incidence of dengue, should be aware of all the diagnostic methods available for routine these days, and choose the one that best suit their working conditions and populations served, in order to save lives. |
format | Text |
id | pubmed-2840934 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-28409342010-03-18 The Laboratorial Diagnosis of Dengue: Applications and Implications Dutra, Nina Rocha de Paula, Marília Barbosa de Oliveira, Michelle Dias de Oliveira, Leandro Licursi De Paula, Sérgio Oliveira J Glob Infect Dis Diagnostics Review The diagnosis of infection by the dengue virus relies, in most cases, on the clinical judgment of the patient, since only a few major centers have clinical laboratories that offer diagnostic tests to confirm the clinical impressions of an infection. At present, routine laboratory diagnosis is done by different kinds of testing. Among them are the methods of serological research, virus isolation, detection of viral antigens, and detection of viral genomes. The continued development of diagnostic tests, which are cheap, sensitive, specific, easy to perform, and capable of giving early diagnosis of the dengue virus infection is still a need. There are also other obstacles that are not specifically related to the technological development of diagnostic methods. For instance, infrastructure of the laboratories, the training of personnel, and the capacity of research of these laboratories are still limited in many parts of Brazil and the world, where dengue is endemic. Clinical laboratories, especially the ones that serve regions with a high incidence of dengue, should be aware of all the diagnostic methods available for routine these days, and choose the one that best suit their working conditions and populations served, in order to save lives. Medknow Publications 2009 /pmc/articles/PMC2840934/ /pubmed/20300385 http://dx.doi.org/10.4103/0974-777X.52980 Text en © Journal of Global Infectious Diseases http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Diagnostics Review Dutra, Nina Rocha de Paula, Marília Barbosa de Oliveira, Michelle Dias de Oliveira, Leandro Licursi De Paula, Sérgio Oliveira The Laboratorial Diagnosis of Dengue: Applications and Implications |
title | The Laboratorial Diagnosis of Dengue: Applications and Implications |
title_full | The Laboratorial Diagnosis of Dengue: Applications and Implications |
title_fullStr | The Laboratorial Diagnosis of Dengue: Applications and Implications |
title_full_unstemmed | The Laboratorial Diagnosis of Dengue: Applications and Implications |
title_short | The Laboratorial Diagnosis of Dengue: Applications and Implications |
title_sort | laboratorial diagnosis of dengue: applications and implications |
topic | Diagnostics Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840934/ https://www.ncbi.nlm.nih.gov/pubmed/20300385 http://dx.doi.org/10.4103/0974-777X.52980 |
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