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Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid

BACKGROUND: High-grade blunt renal trauma has been treated by arterial embolization (AE). However, it is unknown whether AE preserves renal function, because conventional renal function tests reflect total renal function and not the function of the injured kidney alone. Dynamic scintigraphy can asse...

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Autores principales: Morita, Seiji, Inokuchi, Sadaki, Tsuji, Tomoatsu, Fukushima, Tomokazu, Higami, Shigeo, Yamagiwa, Takeshi, Shinichi, Iizuka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841086/
https://www.ncbi.nlm.nih.gov/pubmed/20205949
http://dx.doi.org/10.1186/1757-7241-18-11
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author Morita, Seiji
Inokuchi, Sadaki
Tsuji, Tomoatsu
Fukushima, Tomokazu
Higami, Shigeo
Yamagiwa, Takeshi
Shinichi, Iizuka
author_facet Morita, Seiji
Inokuchi, Sadaki
Tsuji, Tomoatsu
Fukushima, Tomokazu
Higami, Shigeo
Yamagiwa, Takeshi
Shinichi, Iizuka
author_sort Morita, Seiji
collection PubMed
description BACKGROUND: High-grade blunt renal trauma has been treated by arterial embolization (AE). However, it is unknown whether AE preserves renal function, because conventional renal function tests reflect total renal function and not the function of the injured kidney alone. Dynamic scintigraphy can assess differential renal function. METHODS: We performed AE in 17 patients with grade-4 blunt renal trauma and determined their serum creatinine (sCr) level and glomerular filtration rate (GFR; estimated by dynamic scintigraphy) after 3 months. In 4 patients with low GFR of the injured kidney (<20 ml·min(-1)·1.73 m(-2)), the GFR and sCr were measured again at 6 months. Data are presented as median and interquartile range (25th, 75th percentile). RESULTS: The median GFR of the injured kidney, total GFR, and median sCr at 3 months were 29.3 (23.7, 35.3) and 96.8 (79.1, 102.6) ml·min(-1)·1.73 m(-2 )and 0.6 (0.5, 0.7) mg/dl, respectively. In the patients with low GFR (ml·min(-1)·1.73 m(-2)), the median GFR of the injured kidney, total GFR, and median sCr (mg/dl) were 16.2 (15.7, 16.3), 68.7 (61.1, 71.6), and 0.7 (0.7, 0.9), respectively, at 3 months and 34.5 (29.2, 37.0), 90.9 (79.1, 98.8), and 0.7 (0.7, 0.8), respectively, at 6 months. CONCLUSIONS: The function of the injured kidney was preserved in all patients, indicating the efficacy of AE for the treatment of grade-4 blunt renal trauma.
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spelling pubmed-28410862010-03-18 Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid Morita, Seiji Inokuchi, Sadaki Tsuji, Tomoatsu Fukushima, Tomokazu Higami, Shigeo Yamagiwa, Takeshi Shinichi, Iizuka Scand J Trauma Resusc Emerg Med Original Research BACKGROUND: High-grade blunt renal trauma has been treated by arterial embolization (AE). However, it is unknown whether AE preserves renal function, because conventional renal function tests reflect total renal function and not the function of the injured kidney alone. Dynamic scintigraphy can assess differential renal function. METHODS: We performed AE in 17 patients with grade-4 blunt renal trauma and determined their serum creatinine (sCr) level and glomerular filtration rate (GFR; estimated by dynamic scintigraphy) after 3 months. In 4 patients with low GFR of the injured kidney (<20 ml·min(-1)·1.73 m(-2)), the GFR and sCr were measured again at 6 months. Data are presented as median and interquartile range (25th, 75th percentile). RESULTS: The median GFR of the injured kidney, total GFR, and median sCr at 3 months were 29.3 (23.7, 35.3) and 96.8 (79.1, 102.6) ml·min(-1)·1.73 m(-2 )and 0.6 (0.5, 0.7) mg/dl, respectively. In the patients with low GFR (ml·min(-1)·1.73 m(-2)), the median GFR of the injured kidney, total GFR, and median sCr (mg/dl) were 16.2 (15.7, 16.3), 68.7 (61.1, 71.6), and 0.7 (0.7, 0.9), respectively, at 3 months and 34.5 (29.2, 37.0), 90.9 (79.1, 98.8), and 0.7 (0.7, 0.8), respectively, at 6 months. CONCLUSIONS: The function of the injured kidney was preserved in all patients, indicating the efficacy of AE for the treatment of grade-4 blunt renal trauma. BioMed Central 2010-03-07 /pmc/articles/PMC2841086/ /pubmed/20205949 http://dx.doi.org/10.1186/1757-7241-18-11 Text en Copyright ©2010 Morita et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Morita, Seiji
Inokuchi, Sadaki
Tsuji, Tomoatsu
Fukushima, Tomokazu
Higami, Shigeo
Yamagiwa, Takeshi
Shinichi, Iizuka
Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title_full Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title_fullStr Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title_full_unstemmed Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title_short Arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mTechnetium-diethylene triamine pentacetic acid
title_sort arterial embolization in patients with grade-4 blunt renal trauma: evaluation of the glomerular filtration rates by dynamic scintigraphy with 99mtechnetium-diethylene triamine pentacetic acid
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841086/
https://www.ncbi.nlm.nih.gov/pubmed/20205949
http://dx.doi.org/10.1186/1757-7241-18-11
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