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Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)

BACKGROUND: CTBT (7-chlorotetrazolo [5,1-c]benzo[1,2,4]triazine) increases efficacy of commonly used antifungal agents by an unknown mechanism. It increases the susceptibility of Saccharomyces cerevisiae, Candida albicans and Candida glabrata cells to cycloheximide, 5-fluorocytosine and azole antimy...

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Detalles Bibliográficos
Autores principales:	Batova, Monika, Klobucnikova, Vlasta, Oblasova, Zuzana, Gregan, Juraj, Zahradnik, Pavol, Hapala, Ivan, Subik, Julius, Schüller, Christoph
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841119/ https://www.ncbi.nlm.nih.gov/pubmed/20202201 http://dx.doi.org/10.1186/1471-2164-11-153

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