Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

BACKGROUND: Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are le...

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Detalles Bibliográficos
Autores principales: Cárdenas, Graciela, Carrillo-Mezo, Roger, Jung, Helgi, Sciutto, Edda, Hernandez, Jose Luis Soto, Fleury, Agnès
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841125/
https://www.ncbi.nlm.nih.gov/pubmed/20202200
http://dx.doi.org/10.1186/1471-2377-10-16
Descripción
Sumario:BACKGROUND: Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to treatment. CASE PRESENTATION: The clinical and radiological pictures of six Mexican patients non-respondent to cysticidal treatment are presented. CONCLUSIONS: The possible factors involved in the cysticidal non-response are discussed and hints are provided of potentially useful changes to therapeutic protocols.

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