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Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

BACKGROUND: Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are le...

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Autores principales: Cárdenas, Graciela, Carrillo-Mezo, Roger, Jung, Helgi, Sciutto, Edda, Hernandez, Jose Luis Soto, Fleury, Agnès
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841125/
https://www.ncbi.nlm.nih.gov/pubmed/20202200
http://dx.doi.org/10.1186/1471-2377-10-16
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author Cárdenas, Graciela
Carrillo-Mezo, Roger
Jung, Helgi
Sciutto, Edda
Hernandez, Jose Luis Soto
Fleury, Agnès
author_facet Cárdenas, Graciela
Carrillo-Mezo, Roger
Jung, Helgi
Sciutto, Edda
Hernandez, Jose Luis Soto
Fleury, Agnès
author_sort Cárdenas, Graciela
collection PubMed
description BACKGROUND: Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to treatment. CASE PRESENTATION: The clinical and radiological pictures of six Mexican patients non-respondent to cysticidal treatment are presented. CONCLUSIONS: The possible factors involved in the cysticidal non-response are discussed and hints are provided of potentially useful changes to therapeutic protocols.
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spelling pubmed-28411252010-03-18 Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series Cárdenas, Graciela Carrillo-Mezo, Roger Jung, Helgi Sciutto, Edda Hernandez, Jose Luis Soto Fleury, Agnès BMC Neurol Case report BACKGROUND: Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to treatment. CASE PRESENTATION: The clinical and radiological pictures of six Mexican patients non-respondent to cysticidal treatment are presented. CONCLUSIONS: The possible factors involved in the cysticidal non-response are discussed and hints are provided of potentially useful changes to therapeutic protocols. BioMed Central 2010-03-04 /pmc/articles/PMC2841125/ /pubmed/20202200 http://dx.doi.org/10.1186/1471-2377-10-16 Text en Copyright ©2010 Cárdenas et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case report
Cárdenas, Graciela
Carrillo-Mezo, Roger
Jung, Helgi
Sciutto, Edda
Hernandez, Jose Luis Soto
Fleury, Agnès
Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title_full Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title_fullStr Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title_full_unstemmed Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title_short Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series
title_sort subarachnoidal neurocysticercosis non-responsive to cysticidal drugs: a case series
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841125/
https://www.ncbi.nlm.nih.gov/pubmed/20202200
http://dx.doi.org/10.1186/1471-2377-10-16
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