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Selective regain of egfr gene copies in CD44(+)/CD24(-/low )breast cancer cellular model MDA-MB-468
BACKGROUND: Increased transcription of oncogenes like the epidermal growth factor receptor (EGFR) is frequently caused by amplification of the whole gene or at least of regulatory sequences. Aim of this study was to pinpoint mechanistic parameters occurring during egfr copy number gains leading to a...
Autores principales: | Agelopoulos, Konstantin, Greve, Burkhard, Schmidt, Hartmut, Pospisil, Heike, Kurtz, Stefan, Bartkowiak, Kai, Andreas, Antje, Wieczorek, Marek, Korsching, Eberhard, Buerger, Horst, Brandt, Burkhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841141/ https://www.ncbi.nlm.nih.gov/pubmed/20199686 http://dx.doi.org/10.1186/1471-2407-10-78 |
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