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Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils

BACKGROUND: Granulocytes are important in the pathogenesis of several inflammatory diseases. Apoptosis is pivotal in the resolution of inflammation. Apoptosis in malignant cells is induced by histone deacetylase (HDAC) inhibitors, whereas HDAC inhibitors do not usually induce apoptosis in non-malign...

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Detalles Bibliográficos
Autores principales:	Kankaanranta, Hannu, Janka-Junttila, Mirkka, Ilmarinen-Salo, Pinja, Ito, Kazuhiro, Jalonen, Ulla, Ito, Misako, Adcock, Ian M, Moilanen, Eeva, Zhang, Xianzhi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841159/ https://www.ncbi.nlm.nih.gov/pubmed/20181093 http://dx.doi.org/10.1186/1476-9255-7-9

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