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Identification of regulatory elements flanking human XIST reveals species differences

BACKGROUND: The transcriptional silencing of one X chromosome in eutherians requires transcription of the long non-coding RNA gene, XIST. Many regulatory elements have been identified downstream of the mouse Xist gene, including the antisense Tsix gene. However, these elements do not show sequence c...

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Detalles Bibliográficos
Autores principales: Chang, Samuel C, Brown, Carolyn J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841178/
https://www.ncbi.nlm.nih.gov/pubmed/20211024
http://dx.doi.org/10.1186/1471-2199-11-20