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Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements

BACKGROUND: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-test and estimation of fold change between analyzed groups. There are many different preprocessing algorithms for summari...

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Detalles Bibliográficos
Autores principales: Mieczkowski, Jakub, Tyburczy, Magdalena E, Dabrowski, Michal, Pokarowski, Piotr
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841208/
https://www.ncbi.nlm.nih.gov/pubmed/20181266
http://dx.doi.org/10.1186/1471-2105-11-104