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A V530I Mutation in c-KIT Exon 10 Is Associated to Imatinib Response in Extraabdominal Aggressive Fibromatosis

Aggressive fibromatosis (AF) or desmoid tumor is a rare condition, characterized by deep tissue invasion by a monoclonal fibroblastic neoplasm, developed from musculoaponeurotic structures. Surgery is the treatment of choice, but negative margins can hardly been achieved in large tumors, and can lea...

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Detalles Bibliográficos
Autores principales: Kurtz, Jean-Emmanuel, Asmane, Irène, Voegeli, Anne-Claire, Neuville, Agnès, Dufresne, Armelle, Litique, Valère, Chevreau, Christine, Bergerat, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841250/
https://www.ncbi.nlm.nih.gov/pubmed/20339585
http://dx.doi.org/10.1155/2010/458156