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Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients

Symptomatic benign prostatic hyperplasia (BPH) typically occurs in the sixth and seventh decades, and the most frequent obstructive urinary symptoms are hesitancy, decreased urinary stream, sensation of incomplete emptying, nocturia, frequency, and urgency. Various medications, specifically 5-α-redu...

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Autores principales: Carnevale, Francisco Cesar, Antunes, Alberto Azoubel, da Motta Leal Filho, Joaquim Mauricio, de Oliveira Cerri, Luciana Mendes, Baroni, Ronaldo Hueb, Marcelino, Antonio Sergio Zafred, Freire, Geraldo Campos, Moreira, Airton Mota, Srougi, Miguel, Cerri, Giovanni Guido
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841280/
https://www.ncbi.nlm.nih.gov/pubmed/19908092
http://dx.doi.org/10.1007/s00270-009-9727-z
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author Carnevale, Francisco Cesar
Antunes, Alberto Azoubel
da Motta Leal Filho, Joaquim Mauricio
de Oliveira Cerri, Luciana Mendes
Baroni, Ronaldo Hueb
Marcelino, Antonio Sergio Zafred
Freire, Geraldo Campos
Moreira, Airton Mota
Srougi, Miguel
Cerri, Giovanni Guido
author_facet Carnevale, Francisco Cesar
Antunes, Alberto Azoubel
da Motta Leal Filho, Joaquim Mauricio
de Oliveira Cerri, Luciana Mendes
Baroni, Ronaldo Hueb
Marcelino, Antonio Sergio Zafred
Freire, Geraldo Campos
Moreira, Airton Mota
Srougi, Miguel
Cerri, Giovanni Guido
author_sort Carnevale, Francisco Cesar
collection PubMed
description Symptomatic benign prostatic hyperplasia (BPH) typically occurs in the sixth and seventh decades, and the most frequent obstructive urinary symptoms are hesitancy, decreased urinary stream, sensation of incomplete emptying, nocturia, frequency, and urgency. Various medications, specifically 5-α-reductase inhibitors and selective α-blockers, can decrease the severity of the symptoms secondary to BPH, but prostatectomy is still considered to be the traditional method of management. We report the preliminary results for two patients with acute urinary retention due to BPH, successfully treated by prostate artery embolization (PAE). The patients were investigated using the International Prostate Symptom Score, by digital rectal examination, urodynamic testing, prostate biopsy, transrectal ultrasound (US), and magnetic resonance imaging (MRI). Uroflowmetry and postvoid residual urine volume complemented the investigation at 30, 90, and 180 days after PAE. The procedure was performed under local anesthesia; embolization of the prostate arteries was performed with a microcatheter and 300- to 500-μm microspheres using complete stasis as the end point. One patient was subjected to bilateral PAE and the other to unilateral PAE; they urinated spontaneously after removal of the urethral catheter, 15 and 10 days after the procedure, respectively. At 6-month follow-up, US and MRI revealed a prostate reduction of 39.7% and 47.8%, respectively, for the bilateral PAE and 25.5 and 27.8%, respectively, for the patient submitted to unilateral PAE. The early results, at 6-month follow-up, for the two patients with BPH show a promising potential alternative for treatment with PAE.
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spelling pubmed-28412802010-03-26 Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients Carnevale, Francisco Cesar Antunes, Alberto Azoubel da Motta Leal Filho, Joaquim Mauricio de Oliveira Cerri, Luciana Mendes Baroni, Ronaldo Hueb Marcelino, Antonio Sergio Zafred Freire, Geraldo Campos Moreira, Airton Mota Srougi, Miguel Cerri, Giovanni Guido Cardiovasc Intervent Radiol Technical Note Symptomatic benign prostatic hyperplasia (BPH) typically occurs in the sixth and seventh decades, and the most frequent obstructive urinary symptoms are hesitancy, decreased urinary stream, sensation of incomplete emptying, nocturia, frequency, and urgency. Various medications, specifically 5-α-reductase inhibitors and selective α-blockers, can decrease the severity of the symptoms secondary to BPH, but prostatectomy is still considered to be the traditional method of management. We report the preliminary results for two patients with acute urinary retention due to BPH, successfully treated by prostate artery embolization (PAE). The patients were investigated using the International Prostate Symptom Score, by digital rectal examination, urodynamic testing, prostate biopsy, transrectal ultrasound (US), and magnetic resonance imaging (MRI). Uroflowmetry and postvoid residual urine volume complemented the investigation at 30, 90, and 180 days after PAE. The procedure was performed under local anesthesia; embolization of the prostate arteries was performed with a microcatheter and 300- to 500-μm microspheres using complete stasis as the end point. One patient was subjected to bilateral PAE and the other to unilateral PAE; they urinated spontaneously after removal of the urethral catheter, 15 and 10 days after the procedure, respectively. At 6-month follow-up, US and MRI revealed a prostate reduction of 39.7% and 47.8%, respectively, for the bilateral PAE and 25.5 and 27.8%, respectively, for the patient submitted to unilateral PAE. The early results, at 6-month follow-up, for the two patients with BPH show a promising potential alternative for treatment with PAE. Springer-Verlag 2009-11-12 2010-04 /pmc/articles/PMC2841280/ /pubmed/19908092 http://dx.doi.org/10.1007/s00270-009-9727-z Text en © Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2009
spellingShingle Technical Note
Carnevale, Francisco Cesar
Antunes, Alberto Azoubel
da Motta Leal Filho, Joaquim Mauricio
de Oliveira Cerri, Luciana Mendes
Baroni, Ronaldo Hueb
Marcelino, Antonio Sergio Zafred
Freire, Geraldo Campos
Moreira, Airton Mota
Srougi, Miguel
Cerri, Giovanni Guido
Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title_full Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title_fullStr Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title_full_unstemmed Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title_short Prostatic Artery Embolization as a Primary Treatment for Benign Prostatic Hyperplasia: Preliminary Results in Two Patients
title_sort prostatic artery embolization as a primary treatment for benign prostatic hyperplasia: preliminary results in two patients
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841280/
https://www.ncbi.nlm.nih.gov/pubmed/19908092
http://dx.doi.org/10.1007/s00270-009-9727-z
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