Cargando…
Pharmacological Characteristics and Clinical Applications of K201
K201 is a 1,4-benzothiazepine derivative that is a promising new drug with a strong cardioprotective effect. We initially discovered K201 as an effective suppressant of sudden cardiac cell death due to calcium overload. K201 is a nonspecific blocker of sodium, potassium and calcium channels, and its...
Autores principales: | Kaneko, Noboru, Matsuda, Ryuko, Hata, Yoshihito, Shimamoto, Ken |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841427/ https://www.ncbi.nlm.nih.gov/pubmed/19442077 http://dx.doi.org/10.2174/157488409788184972 |
Ejemplares similares
-
K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes
por: Elliott, E. B., et al.
Publicado: (2011) -
K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca(2+) leak from the sarcoplasmic reticulum
por: Toischer, Karl, et al.
Publicado: (2009) -
Memorandum 201
por: CERN. Geneva. Proton Synchrotron and Synchrocyclotron Committee
Publicado: (1984) -
Health Tract, No. 201: Apoplexy
Publicado: (1865) -
Health Tract, No. 201: Apoplexy
Publicado: (1864)