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IFRD1 polymorphisms in cystic fibrosis with potential link to altered neutrophil function
Lung disease is the major cause of morbidity and mortality in cystic fibrosis (CF), an autosomal recessive disease caused by mutations in CFTR. In CF, chronic infection and dysregulated neutrophilic inflammation lead to progressive airway destruction. The severity of CF lung disease has significant...
Autores principales: | Gu, YuanYuan, Harley, Isaac T. W., Henderson, Lindsay B., Aronow, Bruce J., Vietor, Ilja, Huber, Lukas A., Harley, John B., Kilpatrick, Jeffrey R., Langefeld, Carl D., Williams, Adrienne H., Jegga, Anil G., Chen, Jing, Wills-Karp, Marsha, Arshad, S. Hasan, Ewart, Susan L., Thio, Chloe L., Flick, Leah M., Filippi, Marie-Dominique, Grimes, H. Leighton, Drumm, Mitchell L., Cutting, Garry R., Knowles, Michael R., Karp, Christopher L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841516/ https://www.ncbi.nlm.nih.gov/pubmed/19242412 http://dx.doi.org/10.1038/nature07811 |
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