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Regulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk

Drosophila Lnk is the single ancestral orthologue of a highly conserved family of structurally-related intracellular adaptor proteins, the SH2B proteins. As adaptors, they lack catalytic activity but contain several protein–protein interaction domains, thus playing a critical role in signal transduc...

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Detalles Bibliográficos
Autores principales: Slack, Cathy, Werz, Christian, Wieser, Daniela, Alic, Nazif, Foley, Andrea, Stocker, Hugo, Withers, Dominic J., Thornton, Janet M., Hafen, Ernst, Partridge, Linda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841611/
https://www.ncbi.nlm.nih.gov/pubmed/20333234
http://dx.doi.org/10.1371/journal.pgen.1000881