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Enhanced Specific Delivery and Targeting of Oncolytic Sindbis Viral Vectors by Modulating Vascular Leakiness in Tumor

Genetic instability of cancer cells generates resistance after initial responses to chemotherapeutic agents. Several oncolytic viruses have been designed to exploit specific signatures of cancer cells, such as important surface markers or pivotal signaling pathways for selective replication. It is l...

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Detalles Bibliográficos
Autores principales: Tseng, Jen-Chieh, Granot, Tomer, DiGiacomo, Vincent, Levin, Brandi, Meruelo, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841696/
https://www.ncbi.nlm.nih.gov/pubmed/19798121
http://dx.doi.org/10.1038/cgt.2009.70