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Enhanced Specific Delivery and Targeting of Oncolytic Sindbis Viral Vectors by Modulating Vascular Leakiness in Tumor
Genetic instability of cancer cells generates resistance after initial responses to chemotherapeutic agents. Several oncolytic viruses have been designed to exploit specific signatures of cancer cells, such as important surface markers or pivotal signaling pathways for selective replication. It is l...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841696/ https://www.ncbi.nlm.nih.gov/pubmed/19798121 http://dx.doi.org/10.1038/cgt.2009.70 |