VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model

We investigated the roles of critical adhesion molecules ICAM-1 and VCAM-1 in a keratin-14 IL-4 transgenic (Tg) mouse model of atopic dermatitis, the skin lesions of which are characterized by prominent inflammatory cell infiltration, significantly increased mRNAs and proteins of ICAM-1, VCAM-1, E-s...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Lin, Shao-xia, Amin, Sanober, Overbergh, Lut, Maggiolino, Giacomo, Chan, Lawrence S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841723/
https://www.ncbi.nlm.nih.gov/pubmed/20065994
http://dx.doi.org/10.1038/icb.2009.107

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