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Improved network performance via antagonism: From synthetic rescues to multi-drug combinations

Recent research shows that a faulty or sub-optimally operating metabolic network can often be rescued by the targeted removal of enzyme-coding genes – the exact opposite of what traditional gene therapy would suggest. Predictions go as far as to assert that certain gene knockouts can restore the gro...

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Detalles Bibliográficos
Autor principal: Motter, Adilson E
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841822/
https://www.ncbi.nlm.nih.gov/pubmed/20127700
http://dx.doi.org/10.1002/bies.200900128