Cargando…
Why Does Binding of Proteins to DNA or Proteins to Proteins Not Necessarily Spell Function?
[Image: see text] Studies of binding are often question: first, is the observed binding functional, and second, if it is, which function? Is it activation or repression? The first question relates to binding at different sites; the second relates to binding at similar sites. These questions apply to...
Autores principales: | Ma, Buyong, Tsai, Chung-Jung, Pan, Yongping, Nussinov, Ruth |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842019/ https://www.ncbi.nlm.nih.gov/pubmed/20151694 http://dx.doi.org/10.1021/cb900293a |
Ejemplares similares
-
Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets
por: Ma, Buyong, et al.
Publicado: (2007) -
Protein dynamics and conformational selection in bidirectional signal transduction
por: Nussinov, Ruth, et al.
Publicado: (2012) -
Regulating highly dynamic unstructured proteins and their coding mRNAs
por: Ma, Buyong, et al.
Publicado: (2009) -
Why Does Hyperuricemia Not Necessarily Induce Gout?
por: Zhang, Wei-Zheng
Publicado: (2021) -
Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States
por: Miller, Yifat, et al.
Publicado: (2011)