Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells

BACKGROUND: BRCA2 gene expression is tightly regulated during the cell cycle in human breast cells. The expression of BRCA2 gene is silenced at the G0/G1 phase of cell growth and is de-silenced at the S/G2 phase. While studying the activity of BRCA2 gene promoter in breast cancer cells, we discovere...

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Detalles Bibliográficos
Autores principales: Misra, Smita, Sharma, Shvetank, Agarwal, Anupriya, Khedkar, Sheetal V, Tripathi, Manish K, Mittal, Mukul K, Chaudhuri, Gautam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842238/
https://www.ncbi.nlm.nih.gov/pubmed/20202217
http://dx.doi.org/10.1186/1476-4598-9-50

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