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Multimodal investigations of trans-endothelial cell trafficking under condition of disrupted blood-brain barrier integrity

BACKGROUND: Stem cells or immune cells targeting the central nervous system (CNS) bear significant promises for patients affected by CNS disorders. Brain or spinal cord delivery of therapeutic cells is limited by the blood-brain barrier (BBB) which remains one of the recognized rate-limiting steps....

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Detalles Bibliográficos
Autores principales: Marchi, Nicola, Teng, Qingshan, Nguyen, Minh T, Franic, Linda, Desai, Nirav K, Masaryk, Thomas, Rasmussen, Peter, Trasciatti, Silvia, Janigro, Damir
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842276/
https://www.ncbi.nlm.nih.gov/pubmed/20214812
http://dx.doi.org/10.1186/1471-2202-11-34