Structure and Assembly Properties of the N-Terminal Domain of the Prion Ure2p in Isolation and in Its Natural Context

BACKGROUND: The aggregation of the baker's yeast prion Ure2p is at the origin of the [URE3] trait. The Q- and N-rich N-terminal part of the protein is believed to drive Ure2p assembly into fibrils of amyloid nature and the fibrillar forms of full-length Ure2p and its N-terminal part generated i...

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Detalles Bibliográficos
Autores principales: Bousset, Luc, Bonnefoy, Jonathan, Sourigues, Yannick, Wien, Frank, Melki, Ronald
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842292/
https://www.ncbi.nlm.nih.gov/pubmed/20339590
http://dx.doi.org/10.1371/journal.pone.0009760

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