Dinucleotide Weight Matrices for Predicting Transcription Factor Binding Sites: Generalizing the Position Weight Matrix

BACKGROUND: Identifying transcription factor binding sites (TFBS) in silico is key in understanding gene regulation. TFBS are string patterns that exhibit some variability, commonly modelled as “position weight matrices” (PWMs). Though convenient, the PWM has significant limitations, in particular t...

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Detalles Bibliográficos
Autor principal: Siddharthan, Rahul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842295/
https://www.ncbi.nlm.nih.gov/pubmed/20339533
http://dx.doi.org/10.1371/journal.pone.0009722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842295/
https://www.ncbi.nlm.nih.gov/pubmed/20339533
http://dx.doi.org/10.1371/journal.pone.0009722

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