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Dinucleotide Weight Matrices for Predicting Transcription Factor Binding Sites: Generalizing the Position Weight Matrix
BACKGROUND: Identifying transcription factor binding sites (TFBS) in silico is key in understanding gene regulation. TFBS are string patterns that exhibit some variability, commonly modelled as “position weight matrices” (PWMs). Though convenient, the PWM has significant limitations, in particular t...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842295/ https://www.ncbi.nlm.nih.gov/pubmed/20339533 http://dx.doi.org/10.1371/journal.pone.0009722 |