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Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations
BACKGROUND: Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three tria...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842298/ https://www.ncbi.nlm.nih.gov/pubmed/20339536 http://dx.doi.org/10.1371/journal.pone.0009763 |