Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

BACKGROUND: Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three tria...

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Detalles Bibliográficos
Autores principales: Barber, Mathew J., Mangravite, Lara M., Hyde, Craig L., Chasman, Daniel I., Smith, Joshua D., McCarty, Catherine A., Li, Xiaohui, Wilke, Russell A., Rieder, Mark J., Williams, Paul T., Ridker, Paul M., Chatterjee, Aurobindo, Rotter, Jerome I., Nickerson, Deborah A., Stephens, Matthew, Krauss, Ronald M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842298/
https://www.ncbi.nlm.nih.gov/pubmed/20339536
http://dx.doi.org/10.1371/journal.pone.0009763

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