Immune Selection and Within-Host Competition Can Structure the Repertoire of Variant Surface Antigens in Plasmodium falciparum - A Mathematical Model

BACKGROUND: The evolutionary mechanisms structuring the expression pattern of variant surface antigen (VSA) families that allow pathogens to evade immune responses and establish chronic and repeated infections pose major challenges to theoretical research. In Plasmodium falciparum, the best-studied...

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Detalles Bibliográficos
Autores principales: van Noort, Sander P., Nunes, Marta C., Weedall, Gareth D., Hviid, Lars, Gomes, M. Gabriela M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842302/
https://www.ncbi.nlm.nih.gov/pubmed/20339540
http://dx.doi.org/10.1371/journal.pone.0009778

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