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Role of TGF-β1 and MAP Kinases in the Antiproliferative Effect of Aspirin in Human Vascular Smooth Muscle Cells

BACKGROUND: We aimed to test the antiproliferative effect of acetylsalicylic acid (ASA) on vascular smooth muscle cells (VSMC) from bypass surgery patients and the role of transforming growth factor beta 1 (TGF-β1). METHODOLOGY/PRINCIPAL FINDINGS: VSMC were isolated from remaining internal mammary a...

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Detalles Bibliográficos
Autores principales: Redondo, Santiago, Ruiz, Emilio, Gordillo-Moscoso, Antonio, Navarro-Dorado, Jorge, Ramajo, Marta, Carnero, Manuel, Reguillo, Fernando, Rodriguez, Enrique, Tejerina, Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842433/
https://www.ncbi.nlm.nih.gov/pubmed/20339548
http://dx.doi.org/10.1371/journal.pone.0009800