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Nerve Terminal Degeneration Is Independent of Muscle Fiber Genotype in SOD1(G93A) Mice
BACKGROUND: Motor neuron degeneration in SOD1(G93A) transgenic mice begins at the nerve terminal. Here we examine whether this degeneration depends on expression of mutant SOD1 in muscle fibers. METHODOLOGY/PRINCIPAL FINDINGS: Hindlimb muscles were transplanted between wild-type and SOD1(G93A) trans...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842435/ https://www.ncbi.nlm.nih.gov/pubmed/20339550 http://dx.doi.org/10.1371/journal.pone.0009802 |