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“Unlicensed” Natural Killer cells dominate the response to cytomegalovirus infection
Natural killer (NK) cells expressing inhibitory receptors that bind to self-MHC class I are “licensed” or rendered functionally more responsive to stimulation, whereas “unlicensed” NK cells lacking receptors for self-MHC class I are hyporesponsive. Here we show that, contrary to the licensing hypoth...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842453/ https://www.ncbi.nlm.nih.gov/pubmed/20190757 http://dx.doi.org/10.1038/ni.1849 |