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Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations
Mutations of mitochondrial DNA are associated with a wide spectrum of disorders, primarily affecting the central nervous system and muscle function. The specific consequences of mitochondrial DNA mutations for neuronal pathophysiology are not understood. In order to explore the impact of mitochondri...
Autores principales: | Abramov, Andrey Y., Smulders-Srinivasan, Tora K., Kirby, Denise M., Acin-Perez, Rebeca, Enriquez, José Antonio, Lightowlers, Robert N., Duchen, Michael R., Turnbull, Douglass M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842515/ https://www.ncbi.nlm.nih.gov/pubmed/20157008 http://dx.doi.org/10.1093/brain/awq015 |
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