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A versatile 3D culture model facilitates monitoring of astrocytes undergoing reactive gliosis
A major impediment to CNS repair is the glial scar, which forms following damage and is composed mainly of ramified, ‘reactive’ astrocytes that inhibit neuronal regrowth. The transition of astrocytes into this reactive phenotype (reactive gliosis) is a potential therapeutic target, but glial scar fo...
Autores principales: | East, Emma, Golding, Jonathan P, Phillips, James B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842570/ https://www.ncbi.nlm.nih.gov/pubmed/19813215 http://dx.doi.org/10.1002/term.209 |
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