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Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)

Congestive heart failure as a consequence of ischemic heart disease is an increasing medical problem. Notwithstanding the huge advances in the medical and conventional surgical management of heart failure, eventual outcomes remain suboptimal. This 2 part article outlines the magnitude of the problem...

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Detalles Bibliográficos
Autores principales: Shanmugam, Ganesh, Ali, Imtiaz S
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842966/
https://www.ncbi.nlm.nih.gov/pubmed/21037851
http://dx.doi.org/10.2174/157340309789317878
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author Shanmugam, Ganesh
Ali, Imtiaz S
author_facet Shanmugam, Ganesh
Ali, Imtiaz S
author_sort Shanmugam, Ganesh
collection PubMed
description Congestive heart failure as a consequence of ischemic heart disease is an increasing medical problem. Notwithstanding the huge advances in the medical and conventional surgical management of heart failure, eventual outcomes remain suboptimal. This 2 part article outlines the magnitude of the problem, the limitations of conventional therapies as they exist, and the use of newer procedures that directly address the restoration of ventricular pump function. The first part of the article deals with the pathology of different facets of the remodeling process, and the unique anatomy, geometry and flow dynamics as they pertain to ventricular function in the normal as well as the failing heart. It then details the limitations of conventional therapy, thereby laying the basis for the need and evolution of newer surgical procedures and ends with the selection of patients for ventricular restoration procedures and the pitfalls in the choice of patients for such newer techniques.
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spelling pubmed-28429662010-11-01 Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I) Shanmugam, Ganesh Ali, Imtiaz S Curr Cardiol Rev Article Congestive heart failure as a consequence of ischemic heart disease is an increasing medical problem. Notwithstanding the huge advances in the medical and conventional surgical management of heart failure, eventual outcomes remain suboptimal. This 2 part article outlines the magnitude of the problem, the limitations of conventional therapies as they exist, and the use of newer procedures that directly address the restoration of ventricular pump function. The first part of the article deals with the pathology of different facets of the remodeling process, and the unique anatomy, geometry and flow dynamics as they pertain to ventricular function in the normal as well as the failing heart. It then details the limitations of conventional therapy, thereby laying the basis for the need and evolution of newer surgical procedures and ends with the selection of patients for ventricular restoration procedures and the pitfalls in the choice of patients for such newer techniques. Bentham Science Publishers Ltd. 2009-11 /pmc/articles/PMC2842966/ /pubmed/21037851 http://dx.doi.org/10.2174/157340309789317878 Text en © Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Shanmugam, Ganesh
Ali, Imtiaz S
Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title_full Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title_fullStr Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title_full_unstemmed Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title_short Surgical Ventricular Restoration: An Operation To Reverse Remodeling - The Basic Science (Part I)
title_sort surgical ventricular restoration: an operation to reverse remodeling - the basic science (part i)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842966/
https://www.ncbi.nlm.nih.gov/pubmed/21037851
http://dx.doi.org/10.2174/157340309789317878
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