IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana

DNA methylation is an epigenetic mark affecting genes and transposons. We screened for mutations that fail to establish DNA methylation, yielding two mutants termed involved in de novo (idn). IDN1 encodes DMS3, an SMC related protein, IDN2 encodes a novel double stranded RNA binding protein with hom...

Descripción completa

Detalles Bibliográficos
Autores principales: Ausin, Israel, Mockler, Todd C., Chory, Joanne, Jacobsen, Steven E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842998/
https://www.ncbi.nlm.nih.gov/pubmed/19915591
http://dx.doi.org/10.1038/nsmb.1690
_version_ 1782179222677094400
author Ausin, Israel
Mockler, Todd C.
Chory, Joanne
Jacobsen, Steven E.
author_facet Ausin, Israel
Mockler, Todd C.
Chory, Joanne
Jacobsen, Steven E.
author_sort Ausin, Israel
collection PubMed
description DNA methylation is an epigenetic mark affecting genes and transposons. We screened for mutations that fail to establish DNA methylation, yielding two mutants termed involved in de novo (idn). IDN1 encodes DMS3, an SMC related protein, IDN2 encodes a novel double stranded RNA binding protein with homology to SGS3. IDN1 and IDN2 control de novo methylation and siRNA-mediated maintenance methylation and are components of the RNA-directed DNA methylation pathway.
format Text
id pubmed-2842998
institution National Center for Biotechnology Information
language English
publishDate 2009
record_format MEDLINE/PubMed
spelling pubmed-28429982010-06-01 IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana Ausin, Israel Mockler, Todd C. Chory, Joanne Jacobsen, Steven E. Nat Struct Mol Biol Article DNA methylation is an epigenetic mark affecting genes and transposons. We screened for mutations that fail to establish DNA methylation, yielding two mutants termed involved in de novo (idn). IDN1 encodes DMS3, an SMC related protein, IDN2 encodes a novel double stranded RNA binding protein with homology to SGS3. IDN1 and IDN2 control de novo methylation and siRNA-mediated maintenance methylation and are components of the RNA-directed DNA methylation pathway. 2009-11-15 2009-12 /pmc/articles/PMC2842998/ /pubmed/19915591 http://dx.doi.org/10.1038/nsmb.1690 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Ausin, Israel
Mockler, Todd C.
Chory, Joanne
Jacobsen, Steven E.
IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title_full IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title_fullStr IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title_full_unstemmed IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title_short IDN1 and IDN2: two proteins required for de novo DNA methylation in Arabidopsis thaliana
title_sort idn1 and idn2: two proteins required for de novo dna methylation in arabidopsis thaliana
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842998/
https://www.ncbi.nlm.nih.gov/pubmed/19915591
http://dx.doi.org/10.1038/nsmb.1690
work_keys_str_mv AT ausinisrael idn1andidn2twoproteinsrequiredfordenovodnamethylationinarabidopsisthaliana
AT mocklertoddc idn1andidn2twoproteinsrequiredfordenovodnamethylationinarabidopsisthaliana
AT choryjoanne idn1andidn2twoproteinsrequiredfordenovodnamethylationinarabidopsisthaliana
AT jacobsenstevene idn1andidn2twoproteinsrequiredfordenovodnamethylationinarabidopsisthaliana

Ejemplares similares