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Discovery of Unique Lanthionine Synthetases Reveals New Mechanistic and Evolutionary Insights
Lantibiotic synthetases are remarkable biocatalysts generating conformationally constrained peptides with a variety of biological activities by repeatedly utilizing two simple posttranslational modification reactions: dehydration of Ser/Thr residues and intramolecular addition of Cys thiols to the r...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843593/ https://www.ncbi.nlm.nih.gov/pubmed/20351769 http://dx.doi.org/10.1371/journal.pbio.1000339 |