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Binding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species

Changes in gene expression play an important role in evolution, yet the molecular mechanisms underlying regulatory evolution are poorly understood. Here we compare genome-wide binding of the six transcription factors that initiate segmentation along the anterior-posterior axis in embryos of two clos...

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Detalles Bibliográficos
Autores principales:	Bradley, Robert K., Li, Xiao-Yong, Trapnell, Cole, Davidson, Stuart, Pachter, Lior, Chu, Hou Cheng, Tonkin, Leath A., Biggin, Mark D., Eisen, Michael B.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843597/ https://www.ncbi.nlm.nih.gov/pubmed/20351773 http://dx.doi.org/10.1371/journal.pbio.1000343

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