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Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease

BACKGROUND: Oxidative stress is heavily implicated in the pathogenic process of Parkinson's disease. Varying capacity to detoxify radical oxygen species through induction of phase II antioxidant enzymes in substantia nigra may influence disease risk. Here, we hypothesize that variation in NFE2L...

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Detalles Bibliográficos
Autores principales: von Otter, Malin, Landgren, Sara, Nilsson, Staffan, Celojevic, Dragana, Bergström, Petra, Håkansson, Anna, Nissbrandt, Hans, Drozdzik, Marek, Bialecka, Monika, Kurzawski, Mateusz, Blennow, Kaj, Nilsson, Michael, Hammarsten, Ola, Zetterberg, Henrik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843602/
https://www.ncbi.nlm.nih.gov/pubmed/20196834
http://dx.doi.org/10.1186/1471-2350-11-36