Hepatitis B Virus X Protein Impairs Hepatic Insulin Signaling Through Degradation of IRS1 and Induction of SOCS3

BACKGROUND: Hepatitis B virus (HBV) is a major cause of chronic liver diseases, and frequently results in hepatitis, cirrhosis, and ultimately hepatocellular carcinoma. The role of HCV in associations with insulin signaling has been elucidated. However, the pathogenesis of HBV-associated insulin sig...

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Detalles Bibliográficos
Autores principales: Kim, KyeongJin, Kim, Kook Hwan, Cheong, JaeHun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843628/
https://www.ncbi.nlm.nih.gov/pubmed/20351777
http://dx.doi.org/10.1371/journal.pone.0008649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843628/
https://www.ncbi.nlm.nih.gov/pubmed/20351777
http://dx.doi.org/10.1371/journal.pone.0008649

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