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Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation

Cytoplasmic presence of Hsp60, which is principally a nuclear gene-encoded mitochondrial chaperonin, has frequently been stated, but its role in intracellular signaling is largely unknown. In this study, we demonstrate that the cytosolic Hsp60 promotes the TNF-α-mediated activation of the IKK/NF-κB...

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Detalles Bibliográficos
Autores principales:	Chun, Jung Nyeo, Choi, Boae, Lee, Kyung Wha, Lee, Doo Jae, Kang, Dong Hoon, Lee, Joo Young, Song, In Sung, Kim, Hye In, Lee, Sang-Hee, Kim, Hyeon Soo, Lee, Na Kyung, Lee, Soo Young, Lee, Kong-Joo, Kim, Jaesang, Kang, Sang Won
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843631/ https://www.ncbi.nlm.nih.gov/pubmed/20351780 http://dx.doi.org/10.1371/journal.pone.0009422

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