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Differential impact of ageing on cellular and humoral immunity to a persistent murine γ-herpesvirus

BACKGROUND: Oncogenic γ-herpesviruses establish life-long infections in their hosts and control of these latent infections is dependent on continual immune surveillance. Immune function declines with age, raising the possibility that immune control of γ-herpesvirus infection becomes compromised with...

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Detalles Bibliográficos
Autores principales: Yager, Eric J, Kim, In-Jeong, Freeman, Michael L, Lanzer, Kathleen G, Burkum, Claire E, Cookenham, Tres, Woodland, David L, Blackman, Marcia A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843645/
https://www.ncbi.nlm.nih.gov/pubmed/20181071
http://dx.doi.org/10.1186/1742-4933-7-3