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Systems genetics analyses predict a transcription role for P2P-R: Molecular confirmation that P2P-R is a transcriptional co-repressor

BACKGROUND: The 250 kDa P2P-R protein (also known as PACT and Rbbp6) was cloned over a decade ago and was found to bind both the p53 and Rb1 tumor suppressor proteins. In addition, P2P-R has been associated with multiple biological functions, such as mitosis, mRNA processing, translation and ubiquit...

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Detalles Bibliográficos
Autores principales: Peidis, Philippos, Giannakouros, Thomas, Burow, Matthew E, Williams, Robert W, Scott, Robert E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843647/
https://www.ncbi.nlm.nih.gov/pubmed/20184719
http://dx.doi.org/10.1186/1752-0509-4-14