Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

BACKGROUND: Activation of Toll-like receptors (TLRs) is widely accepted as an essential event for defence against infection. Many TLRs utilize a common signalling pathway that relies on activation of the kinase IRAK4 and the transcription factor NFκB for the rapid expression of immunity genes. METHO...

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Detalles Bibliográficos
Autores principales: Brown, Kelly L, Falsafi, Reza, Kum, Winnie, Hamill, Pamela, Gardy, Jennifer L, Davidson, Donald J, Turvey, Stuart, Finlay, Brett B, Speert, David P, Hancock, Robert EW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843650/
https://www.ncbi.nlm.nih.gov/pubmed/20105294
http://dx.doi.org/10.1186/1479-5876-8-6

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