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A New α(5)β(1) Integrin-Dependent Survival Pathway Through GSK3β Activation in Leukemic Cells
BACKGROUND: Cell survival mediated by integrin engagement has been implicated in cell adhesion-mediated drug resistance. We have recently demonstrated that the activation of glycogen synthase kinase 3 β (GSK3β) is a new pathway supporting the chemoresistance of leukemic cells adhered to fibronectin....
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843713/ https://www.ncbi.nlm.nih.gov/pubmed/20352103 http://dx.doi.org/10.1371/journal.pone.0009807 |