Cargando…
Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines
Cystatin C (CysC) expression in the brain is elevated in human patients with epilepsy, in animal models of neurodegenerative conditions, and in response to injury, but whether up-regulated CysC expression is a manifestation of neurodegeneration or a cellular repair response is not understood. This s...
Autores principales: | Tizon, Belen, Sahoo, Susmita, Yu, Haung, Gauthier, Sebastien, Kumar, Asok R., Mohan, Panaiyur, Figliola, Matthew, Pawlik, Monika, Grubb, Anders, Uchiyama, Yasuo, Bandyopadhyay, Urmi, Cuervo, Ana Maria, Nixon, Ralph A., Levy, Efrat |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843718/ https://www.ncbi.nlm.nih.gov/pubmed/20352108 http://dx.doi.org/10.1371/journal.pone.0009819 |
Ejemplares similares
-
Neuroprotection mediated by cystatin C-loaded extracellular vesicles
por: Pérez-González, Rocío, et al.
Publicado: (2019) -
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
por: Yu, W. Haung, et al.
Publicado: (2005) -
Cystatin C in Alzheimer's disease
por: Kaur, Gurjinder, et al.
Publicado: (2012) -
Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis
por: Li, Wei, et al.
Publicado: (2016) -
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
por: Bordi, Matteo, et al.
Publicado: (2016)