Cargando…

Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice

Heat shock proteins have been implicated as endogenous activators for dendritic cells (DCs). Chronic expression of heat shock protein gp96 on cell surfaces induces significant DC activations and systemic lupus erythematosus (SLE)-like phenotypes in mice. However, its potential as a therapeutic targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Jung Min, Kwon, Nam Hoon, Lee, Jin Young, Jeong, Seung Jae, Jung, Hee Jung, Kim, Hyeong Rae, Li, Zihai, Kim, Sunghoon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843739/
https://www.ncbi.nlm.nih.gov/pubmed/20352117
http://dx.doi.org/10.1371/journal.pone.0009792