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Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice
Heat shock proteins have been implicated as endogenous activators for dendritic cells (DCs). Chronic expression of heat shock protein gp96 on cell surfaces induces significant DC activations and systemic lupus erythematosus (SLE)-like phenotypes in mice. However, its potential as a therapeutic targe...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843739/ https://www.ncbi.nlm.nih.gov/pubmed/20352117 http://dx.doi.org/10.1371/journal.pone.0009792 |