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JAK3/STAT5/6 Pathway Alterations Are Associated with Immune Deviation in CD8(+) T Cells in Renal Cell Carcinoma Patients

To investigate the molecular mechanisms underlying altered T cell response in renal cell carcinoma (RCC) patients, we compared autologous and allogeneic CD8(+) T cell responses against RCC line from RCC patients and their HLA-matched donors, using mixed lymphocyte/tumor cell cultures (MLTCs). In add...

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Detalles Bibliográficos
Autores principales:	Cavalcanti, Elisabetta, Gigante, Margherita, Mancini, Vito, Battaglia, Michele, Ditonno, Pasquale, Capobianco, Carmela, Cincione, Raffaele I., Selvaggi, Francesco P., Herr, Wolfgang, Storkus, Walter J., Gesualdo, Loreto, Ranieri, Elena
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843943/ https://www.ncbi.nlm.nih.gov/pubmed/20339477 http://dx.doi.org/10.1155/2010/935764

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