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Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression

Lysophosphatidic acid (LPA) is a potent lipid mediator that acts on a series of specific G protein-coupled receptors, leading to diverse biological actions. Lysophosphatidic acid induces cell proliferation, survival and migration, which are critically required for tumour formation and metastasis. Th...

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Detalles Bibliográficos
Autores principales: Panupinthu, N, Lee, H Y, Mills, G B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844037/
https://www.ncbi.nlm.nih.gov/pubmed/20234370
http://dx.doi.org/10.1038/sj.bjc.6605588