TILRR, a Novel IL-1RI Co-receptor, Potentiates MyD88 Recruitment to Control Ras-dependent Amplification of NF-κB

Host defense against infection is induced by Toll-like and interleukin (IL)-1 receptors, and controlled by the transcription factor NF-κB. Our earlier studies have shown that IL-1 activation impacts cytoskeletal structure and that IL-1 receptor (IL-1RI) function is substrate-dependent. Here we ident...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Shephard, Freya, Kim, Hong B., Palmer, Ian R., McHarg, Selina, Fowler, Gregory J. S., O'Neill, Luke A. J., Kiss-Toth, Endre, Qwarnstrom, Eva E.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844171/
https://www.ncbi.nlm.nih.gov/pubmed/19940113
http://dx.doi.org/10.1074/jbc.M109.073429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844171/
https://www.ncbi.nlm.nih.gov/pubmed/19940113
http://dx.doi.org/10.1074/jbc.M109.073429

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