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Proteoliposomes Harboring Alkaline Phosphatase and Nucleotide Pyrophosphatase as Matrix Vesicle Biomimetics

We have established a proteoliposome system as an osteoblast-derived matrix vesicle (MV) biomimetic to facilitate the study of the interplay of tissue-nonspecific alkaline phosphatase (TNAP) and NPP1 (nucleotide pyrophosphatase/phosphodiesterase-1) during catalysis of biomineralization substrates. F...

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Detalles Bibliográficos
Autores principales: Simão, Ana Maria S., Yadav, Manisha C., Narisawa, Sonoko, Bolean, Mayte, Pizauro, Joao Martins, Hoylaerts, Marc F., Ciancaglini, Pietro, Millán, José Luis
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844207/
https://www.ncbi.nlm.nih.gov/pubmed/20048161
http://dx.doi.org/10.1074/jbc.M109.079830